Does apricot seeds consumption cause changes in human urine?

Authors

  • Eva Tušimová Slovak University of Agriculture, Research Centre AgroBioTech, Tr. A. Hlinku 2, 94976 Nitra
  • Anton Kováčik Slovak University of Agriculture, Faculty of Biotechnology and Food Sciences, Department of Animal Physiology, Tr. A. Hlinku 2, 949 76 Nitra
  • Marek Halenár Slovak University of Agriculture, Faculty of Biotechnology and Food Sciences, Department of Animal Physiology, Tr. A. Hlinku 2, 949 76 Nitra
  • Katarí­na Michalcová Slovak University of Agriculture, Faculty of Biotechnology and Food Sciences, Department of Animal Physiology, Tr. A. Hlinku 2, 949 76 Nitra
  • Katarí­na Zbyňovská Slovak University of Agriculture, Faculty of Biotechnology and Food Sciences, Department of Animal Physiology, Tr. A. Hlinku 2, 949 76 Nitra
  • Anna Kolesárová Slovak University of Agriculture, Faculty of Biotechnology and Food Sciences, Department of Plant Products Storage and Processing, Tr. A. Hlinku 2, 949 76 Nitra
  • Jana Kopčeková Slovak University of Agriculture, Faculty of Agrobiology and Food Resources, Department of Human Nutrition, Tr. A. Hlinku 2, 949 76 Nitra
  • Jozef Valuch Health Care Surveillance Authority, Žellova 2, 829 24 Bratislava
  • Adriana Kolesárová Slovak University of Agriculture, Faculty of Biotechnology and Food Sciences, Department of Animal Physiology, Tr. A. Hlinku 2, 949 76 Nitra

DOI:

https://doi.org/10.5219/755

Keywords:

amygdalin, apricot seed, urine, minerals, urea

Abstract

Natural substances, such as amygdalin, used in alternative medicine gained high popularity. Common people as well as patients with different diseases have almost unlimited access to various natural supplements. To protect human health, it is very important to study effect of these substances. Amygdalin is a cyanogenic glucoside derived from seeds of rosaceous plants, for example seeds of bitter almonds (Prunus dulcis), or apricot, cherry, apple, peach, plum, etc. It is a natural product that owns antitumor activity, it has also been used for the treatment of asthma, bronchitis, emphysema, leprosy and diabetes and produces a kind of antitussive and antiasthmatic effects. The present in vivo study was designed to reveal whether amygdalin in apricot seeds has got an effect on human urine composition, pH value and urine associated health status after six weeks of oral administration. The study group finally consisted of 34 healthy adult volunteers (21 females and 13 males). All participants were asked to consume 60 mg.kg-1 body weight of bitter apricot seeds daily (approximately 3.0 mg.kg-1 of amygdalin) during 6 weeks. During the experiment, three urine collections were carried out (first collection - at the beginning of the experiment; second collection - after 21 days; third collection - after 42 days). Quantification of urine calcium (Ca), magnesium (Mg), phosphorus (P), sodium (Na), potassium (K), chlorides (Cl-), urea and pH value after apricot seeds supplementation was performed. Statistical analysis of variance showed, that consumption of bitter apricot seeds during 42 days had a significant (p <0.01) effect on amount of calcium excreted in urine, though this decrease shifted its level from elevated mean value in control collection into normal physiological range. Significant changes were observed in urea (p <0.05) and phosphorus (p <0.01) levels in urine after apricot seed ingestion, but gender was also considered to be a source of their variation.

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Published

2017-04-19

How to Cite

Tušimová, E. ., Kováčik, A. ., Halenár, M. ., Michalcová, K. ., Zbyňovská, K. ., Kolesárová, A. ., Kopčeková, J. ., Valuch, J. ., & Kolesárová, A. . (2017). Does apricot seeds consumption cause changes in human urine?. Potravinarstvo Slovak Journal of Food Sciences, 11(1), 244–251. https://doi.org/10.5219/755

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