Potravinarstvo, Vol 6, No 1 (2012)

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Zuzana Hladíková, Jana Smetanková, Gabriel Greif, Mária Greifová


Lactococcus lactis species is one of the most important groups of lactic acid bacteria that are used in the dairy industry. Lactococci are generally found on plants and the skins of animals. Special interest is placed on the study of Lactococcus lactis ssp. lactis and Lactococcus lactis ssp. cremoris, as they are the strains used as starter cultures in industrial dairy fermentation. The major functions of this species in dairy fermentation are the production of lactic acid, formation of flavour and aroma compounds, development of ripened cheese texture and antimicrobial activity against spoilage bacteria and moulds.


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ADAMBERG, K., KASK, S., LAHT, T. M., PAALME, T. 2003. The effect of temperature and pH on the growth of lactic acid bacteria: a pH-auxostat study. In International Journal of Food Microbiology, vol. 85, 2003, p. 171-183. doi:10.1016/S0168-1605(02)00537-8 PMid:12810281

AMMOR, M. S., FLÓREZ, A. B., MAYO, B. 2007. Antibiotic resistance in non-enterococcal lactic acid bacteria and bifidobacteria. In Food Microbiology, vol.  24, 2007, p. 559-570. doi:10.1016/j.fm.2006.11.001 PMid:17418306

AYALA-HERNÁNDEZ, I., HASSAN, A. N., GOFF, H. D., MIRA DE ORDUNA, R., CORREDIG, M. 2008. Production, isolation and characterization of exopolysaccharides produced by Lactococcus lactis subsp. cremoris JFR1 and their interaction with milk proteins: Effect of pH and media composition. In International Dairy Journal, vol. 18, 2008, p. 1109-1118. doi:10.1016/j.idairyj.2008.06.008

AYALA-HERNÁNDEZ, I., HASSAN, A. N., GOFF, H. D., CORREDIG, M. 2009. Effect of protein supplementation on the rheological characteristics of milk permeates fermented with exopolysaccharide-producing Lactococcus lactis subsp. cremoris. In Food Hydrocolloids, vol. 23, 2009, p. 1299-1304. doi:10.1016/j.foodhyd.2008.11.004

BALCÁZAR, J. L., VENDRELL, D., DE BLAS, I., RUIZ-ZARZUELA, I., MUZQIZ, J. L., GIRONES, O. 2008. Characterization of probiotic properties of lactic acid bacteria isolated from intestinal microbiota of fish. In Aquaculture, vol. 278, 2008, p. 188-191. doi:10.1016/j.aquaculture.2008.03.014

BATISH, V. K., ROY, U., LAL, R., GROVER, S. 2009. Antifungal attributes of lactic acid bacteria - A review. In Critical Reviews in Biotechnology, vol. 17, 1997, p. 2009-2225. PMid:9306649

BERESFORD, T. P., FITZSIMONS, N. A., BRENNAN, N. L., COGAN, T. M. 2001. Recent advances in cheese microbiology. In International Dairy Journal, vol. 11, 2001, p. 259-274. doi:10.1016/S0958-6946(01)00056-5

BIBAL, B., GOMA, G., VAYSSIER, Y., PAREILLEUX, A. 1988.  Influence of pH, lactose and lactic acid on the growth of Streptococcus cremoris: a kinetic study. In Applied Microbiology and Biotechnology, vol. 28, 1988, p. 340-344. doi:10.1007/BF00268192

BOVER-CID, S., HUGAS, M., IZQUIERDO-PULIDO, M., VIDAL-CAROU, M. C. 2001. Amino acid-decarboxylase activity of  bacteria isolated from fermented pork sausages.  In International Journal of Food Microbiology, vol. 66, 2001, p. 185-189. doi:10.1016/j.fm.2007.10.013

BOVER-CID, S., MIGUÉLEZ-ARRIZADO, M. J., BECKER, B., HOLZAPFEL, W. H., CARMEN, M., VIDAL-CAROU, M. C. 2008. Amino acid decarboxylation by Lactobacillus curvatus CTC273 affected by the pH and glucose availability. In Food Microbiology, vol. 25, 2008, p. 269-277. doi:10.1016/j.fm.2007.10.013 PMid:18206769

BUŇKOVÁ, L., BUŇKA, F., POLLAKOVÁ, E., PODEŠVOVÁ, T., DRÁB, V., KRÁČMAR, S. 2010. Effect of aero-/anaerobiosis on decarboxylase activity of selected lactic acid bacteria. In Potravinarstvo, vol. 4, 2010, p. 5-7. doi:10.5219/43

BUŇKOVÁ, L., BUŇKA, F., HLOBILOVÁ, M., VANÁTKOVÁ, Z., NOVÁKOVÁ, D., DRÁB, V. 2009. Tyramine production of technological important strains of Lactobacillus, Lactococcus and Streptococcus. In European Food Research and Technology, vol. 229, 2009, p. 533-538. doi:10.1007/s00217-009-1075-3

CACHON, R., DIVIÉS, C. 1994. Generalized model of the effect of pH on lactate fermentation and citrate bioconversion in Lactococcus lactis ssp. lactis biovar diacetylactis. In Applied Microbiology and  Biotechnology, vol. 41, 1994,  p. 694-699. doi:10.1007/BF00167287

CASALTA, E., MONTEL, M. CH. 2008. Safety assessment of dairy microorganisms: The Lactococcus genus. In International Journal of Food Microbiology, vol. 126, 2008, p. 271-273. doi:10.1016/j.ijfoodmicro.2007.08.013 PMid:17976847

CASTELLANO, P., BELFIORE, C., FADDA, S., VIGNOLO, G. 2008. A review of bacteriocinogenic lactic acid bacteria used as bioprotective cultures in fresh meat produced in Argentina. In Meat Science, vol. 79, 2008, p. 483-499. doi:10.1016/j.meatsci.2007.10.009 PMid:22062909

CORROLER, D., DESMASURES, N., GUEGUEN, M. 1999. Correlation between polymerase chain reaction of analysis of the histidine biosynthesis operon, randomly amplified polymorphic DNA analysis and phenotypic characterization of dairy Lactococcus isolates.  In Applied Microbiology and Biotechnology, vol. 51, 1999, p. 91-99. doi:10.1007/s002530051368 PMid:10077825

DE VUYST, L., DEGEEST, B. 1999. Heteropolysaccharides from lactic acid bacteria. In FEMS Microbiology Reviews, vol. 23, 1999, p. 153-177. doi:10.1016/j.ijfoodmicro.2008.08.015 PMid:18845350

EMBORG, J., DALGAARD, P. 2008. Growth, inactivation and histamine formation of Morganella psychrotolerans and Morganella morganii - development and evaluation of predictive models. In International Journal of Food Microbiology, vol. 128, 2008, p. 234-243. doi:10.1016/j.ijfoodmicro.2008.08.015 PMid:18845350

FERNÁNDEZ, M., LINARES, D. M., RODRÍGUES, A., ALVAREZ, M. A. 2007. Factors affecting tyramine production in Enterococcus durans IPLA 655. In Applied Microbiology and Biotechnology, vol. 73, 2007, p. 1400-1406. doi:10.1007/s00253-006-0596-y PMid:17043827

FLÓREZ, A. B., DELGADO, S., MAYO, B. 2005.  Antimicrobial susceptibility of lactic acid bacteria isolated from a cheese environment. In Canadian Journal of Microbiology, vol. 51, 2005, p. 51-58. doi:10.1139/w04-114 PMid:15782234

FOLKENBERG, D. M., DEJMEK, P., SKRIVER, A., IPSEN, R. 2005. Relation between sensory texture properties and exopolysaccharide distribution in set and in stirred yogurts produced with different starter cultures.  In Journal of Texture Studies, vol. 36, 2005, p. 174-189. doi:10.1111/j.1745-4603.2005.00010.x

GÁLVEZ, A., LOPEZ, R. L., ABRIOUEL, H., VALDIVIA, E., OMAR, N. B. 2008. Application of bacteriocins in the control of foodborne pathogenic andspoilage bacteria. In Critical Reviews in Biotechnology, vol. 28, 2008,  p. 125-152. doi:10.1080/07388550802107202 PMid:18568851

GARDINI, F., MARTUSCELLI, M., CARUSO, M. C., GALGANO, F., CRUDELE, M. A., FAVATI, F., GUERZONI, M. E., SUZZI, G. 2001. Effects of pH, temperature and NaCl concentration on the growth kinetics, proteolytic activity and biogenic amine production of Enterococcus faecalis. In International Journal of Food Microbiology, vol. 64, 2001, p. 105-117. doi:10.1016/S0168-1605(00)00445-1 PMid:11252492

GARDINI, F., ZACCARELLI, A., BELLETI, N., FAUSTINI, F., CAVAZZA, A., MARTUSCELLI, M., MASTROCOLA, D., SUZZI, G. 2005. Factors influencing biogenic amine production by a strain of Oenococcus oeni in a model system. In Food Control, vol. 16, 2005, p. 609-616. doi:10.1016/j.foodcont.2004.06.023

GARRIGA, M., PASCUAL, M., MONFORT, J. M., HUGAS, M. 1998. Selection of lactobacilli for chicken probiotic adjuncts. In Journal of Applied Microbiology, vol. 84, 1998, p. 125-132. doi:10.1046/j.1365-2672.1997.00329.x PMid:15244067

GONZÁLES, L., SACRISTÁN, N., ARENAS, R., FRESNO, J. M., TORNADIJO, M. E. 2010. Enzymatic activity of lactic acid bacteria (with antimicrobial properties) isolated from a traditional Spanish cheese. In Food Microbiology, vol. 27, 2010, p. 592-597. doi:10.1016/j.fm.2010.01.004 PMid:20510776

GONZÁLES, L., SANDOVAL, H., SACRISTÁN, N., CASTRO, J. M., FRESNO, J. M., TORNADIJO, M. E. 2007. Identification of lactic acid bacteria isolated from Genestoso cheese throughout ripening and study of their antimicrobial activity. In Food Control, vol. 18, 2007, p. 716-722. doi:10.1016/j.foodcont.2006.03.008

GÖRNER, F., VALÍK, Ľ. 2004. Aplikovaná mikrobiológia požívatín. Malé centrum : Bratislava, 2004, 528 p.

GREIF, G., GREIFOVÁ, M., KAROVIČOVÁ, J. 2006. Effects of  NaCl concentration and initial pH value on biogenic amine formation dynamics by Enterobacter spp. bacteria in model conditions. In Journal of Food and Nutrition Research, vol. 45, 2006, p. 21-29.

GREIF, G., GREIFOVÁ, M., KAROVIČOVÁ, J. 1997. Tvorba kadaverínu a amoniaku činnosťou  niektorých baktérií za modelových podmienok. In Czech Journal of Food Science, 16, 1997, p. 53-56.

GREIF, G., GREIFOVÁ, M. 2006. Štúdium analýzy biogénnych amínov vo vybraných mliečnych výrobkoch. In Mliekarstvo, vol. 37, 2006, p. 38- 42.

GREIFOVÁ, M., KRAJČOVÁ, E., GREIF, G., PAGURKO, A., SCHMIDT, S. 2008. Antimikrobiálna aktivita Lactobacillus reuteri a produkty metabolizmu počas fermentácie glycerolu. In Mliekarstvo, vol. 39, 2008, p. 19-24.

GROBBEN, G. J., CHIN-JOE, I., KITZEN, V. A., BOELS, I. C., BOER, F., SIKKEMA, J. 1998. Enhancement of exopolysaccharide production by Lactobacillus delbrueckii subsp. bulgaricus NCFB 2772 with a simplified defined medium. In Applied and Environmental Microbiology, vol. 64, 1998, p. 1333-1337. PMid:16349540

HAINES, W. C., HARMON, L. G. 1973. Effect of selected lactic acid bacteria on growth of Staphylococcus aureus and production of enterotoxin.  In Applied Microbiology, vol. 25, 1973a, p. 436-441.  PMid:4633430 

HAINES, W. C., HARMON, L. G. 1973. Effect of variations in conditions of incubation upon inhibition of Staphylococcus aureus by Pediococcus cerevisiae and Streptococcus lactis. In Applied Microbiology, vol. 25, 1973b, p. 169-172. PMid:4632847

HASSAN, A. N., FRANK, J. F., ELSODA, M. 2003. Observation of bacterial exopolysaccharide in dairy products using cryo-scanning electron microscopy. In International Dairy Journal, vol. 13, 2003, p. 755-762. doi:10.1016/S0958-6946(03)00101-8

HASSAN, A. N., FRANK, J. F., SCHMIDT, K. A., SHALABI, S. I. 1996. Rheological properties of yogurt made with encapsulated nonropy lactic cultures. In Journal of Dairy Science, vol.79, 1996, p. 2091-2097. doi.org/10.3168/jds.S0022-0302(96)76582-7

HERRERO, M., MAYO, B., GONZÁLES, B., SUÁREZ, J. E. 1996. Evaluation of technologically important traits in lactic acid bacteria isolated from spontaneous fermentations. In Journal of Applied Bacteriology, vol. 81, 1996, p. 565-570. doi:10.1111/j.1365-2672.1996.tb03548.x

CHAMPAGNE, C. P., GAGNON, D., ST-GELAIS, D., VUILLEMARD, J. C. 2009. Interactions between Lactococcus lactis and Streptococcus thermophilus strains in Cheddar cheese processing conditions. In International Dairy Journal, vol. 19, 2009, p. 669-674. doi:10.1016/j.idairyj.2009.06.002

CHARLIER, C., EVEN, S., GAUTIER, M., LE LOIR, Y. 2008. Acidification is not involved in the early inhibition of Staphylococcus aureus growth by Lactococcus lactis in milk. In International Dairy Journal, vol. 18, 2008, p. 197-203. doi:10.1016/j.idairyj.2007.03.015

CHAVES, A. C., FERNANDÉZ, M., LERAYER, A. L., MIERAU, I., KLEEREBEZEM, M., HUGENHOLTZ, J. 2002. Metabolic engineering of acetaldehyde production by Streptococcus thermophilus. In Applied and Environmental Microbiology, vol. 68, 2002,  p. 5656-5662. doi:10.1128/AEM.68.11.5656-5662.2002 PMid:12406762

IYER, R., TOMAR, S. K., MAHESWARI, T. U., SINGH, R. 2010. Streptococcus thermophilus strains: Multifunctional lactic acid bacteria. In International Dairy Journal, vol. 20, 2010, p. 133-141. doi:10.1016/j.idairyj.2009.10.005

JEANSON, S., HILGERT, N., COQUILLARD, M. O., SEUKPANYA, C., FAIVELEY, M., NEVEU, P., ABRAHAM, CH., GEORGESCU, V., FOURCASSIÉ, P., BEUVIER, E. 2009. Milk acidification by Lactococcus lactis is improved by decreasing the level of dissolved oxygen rather than decreasing redox potential in the milk prior to inoculation. In International Journal of Food Microbiology, vol. 131, 2009, p. 75-81. doi:10.1016/j.ijfoodmicro.2008.09.020 PMid:18986723

JIN, L. Z., HO, Y. W., ABDULLAH, N., JALALUDIN, S. 1998. Acid and bile tolerance of Lactobacillus isolated from chicken intestine. In Letters in Applied Microbiology, vol. 27, 1998,  p. 183-185. doi:10.1046/j.1472-765X.1998.00405.x PMid:9750324

JUILLARD, V., LA BARS, D., KUNJI, E. R. S., KONINGS, W. N., RICHARD, J. 1995. Oligopeptides are the main source of nitrogen for Lactococcus lactis growth in milk. In Applied and Enviromental Microbiology, vol. 61, 1995, p. 3024-3010. PMid:7487034

KHEDID, K., FAID, M., MOKHTARI, A., SOULAYMANI, A.,  ZINEDINE, A. 2009. Characterization of lactic acid bacteria isolated from the one humped camel milk produced in Morocco. In Microbiological Research, vol. 164, 2009, p. 81-91. doi:10.1016/j.micres.2006.10.008 PMid:17187971

KIMOTO, H., NOMURA, M., KOBAYASHI, M., MIZUMACHI, K., OKAMOTO, T. 2003. Survival of lactococci during passage through mouse digestive tract. In Canadian Journal of Microbiology, vol. 49, 2003,  p. 707-711. doi:10.1139/w03-092 PMid:14735220

KIMOTO-NIRA, H., KOBAYASHI, M., NOMURA, M., SASAKI, K., SUZUKI, CH. 2009. Bile resistance in Lactococcus lactis strains varies with cellular fatty acid composition: analysis by using different growth media. In International Journal of Food Microbiology, vol. 131, 2009, p. 183-188. doi:10.1016/j.ijfoodmicro.2009.02.021 PMid:19339076

KIMOTO-NIRA, H., SUZUKI, CH. SASAKI, K., KOBAYASHI, M., MIZUMACHI, K. 2010. Survival of a Lactococcus lactis strain varies with its carbohydrate preference under in vitro conditions simulated gastrointestinal tract. In International Journal of Food Microbiology, vol. 143, 2010, p. 226-229. doi:10.1016/j.ijfoodmicro.2010.07.033 PMid:20810182

KLIJN, N., WEERKAMP, A. H., DE VOS, W. M. 1995. Genetic marking of Lactococcus lactis shows its survival in the human gastrointestinal tract. In Applied and Environmental Microbiology, vol. 61, 1995, p. 2771-2774. PMid:7618890

KOLOŠTA, M. 1998. Vplyv faktorov prvovýroby na vhodnosť mlieka na výrobu syrov. In Mliekarstvo, vol. 29, 1998. p. 21-24.

KRIZKOVA, L., ZITNANOVA, I., MISLOVICOVA, D., MASAROVA, J., SASINKOVA, V., DURACKOVA, Z., KRAJCOVIC, J. 2006. Antioxidant and antimutagenic activity of mannan neoglycoconjugates: Mannan-human serum albumine and mannan-penicillin G acylase. In Mutation Research, vol. 606, 2006, p. 72-79. doi.org/10.1016/j.mrgentox.2006.03.003 PMid:16677851

KUNJI, E. R. S., MIERAU, I., HAGTING, A., POOLMAN, B., KONINGS, W. N. 1996. The proteolytic system of lactic acid bacteria.  In Antonie van Leeuwenhoek, vol. 70, 1996, p. 187-221. doi:10.1007/BF00395933 PMid:8879407

LANDETE, J. M., FERRER, S., PARDO, I. 2007. Biogenic amine production by lactic acid bacteria, acetic bacteria and yeast isolated from wine. In Food Control, vol. 18, 2007, p. 1569-1574. doi:10.1016/j.foodcont.2006.12.008

LAWS, A. P., GU, Y., MARSHALL, V. M. 2001. Biosynthesis, characterization and design of bacterial exopolysaccharides from lactic acid bacteria. In Biotechnology Advances, vol. 19, 2001, p. 597-625. doi:10.1016/S0734-9750(01)00084-2 PMid:14550013

LEE, D. A., COLLINS, E. B. 1976. Influence of temperature on growth of Streptococcus cremorisStreptococcus lactis. In Journal of  Dairy Science, vol. 59, 1976, p. 405-409. doi:10.3168/jds.S0022-0302(76)84220-8 PMid:1208408

LEE, H. J., JOO, Y. L., PARK, C. H., KIM, S. H., HWANG, I., AHN, J. G., HHEEN, T.I. 1999. Purification and characterization of a bacteriocin produced by L. lactis subsp. lactis H559 isolated from kimchi. In Journal of Bioscience and Bioengineering, vol. 88, 1999, p. 153-159. doi:10.1016/S1389-1723(99)80194-7 PMid:16232590

LEVY, S. B., MARSHALL, B. 2004. Antibacterial resistance world wide: causes, challenges and responses. In Nature Medicine, vol. 10, 2004, p. 122-129. doi:10.1038/nm1145 PMid:15577930

MACEDO, M. G., LACROIX, C., GARDNER, N. J., CHAMPAGNE, C. P. 2002. Effect of medium supplementation on exopolysaccharide production by Lactobacillus rhamnosus RW-9595M in whey permeate. In International Dairy Journal, vol. 12, 2002, p. 419-426. doi:10.1016/S0958-6946(01)00173-X

MC CUE, P., SHETTY, K. 2002. A biochemical analysis of mungbean (Vigna radiata) response to microbial polysaccharides and potential phenolic-enhancing effects for nutraceutical applications. In Food Biotechnology, vol. 16, 2002, p. 57-79. doi:10.1081/FBT-120004201

NORMARK, B. H., NORMARK, S. 2002. Evolution and spread of antibiotic resistance. In Journal of Internal Medicine, vol. 252, 2002, p. 91-106. doi:10.1046/j.1365-2796.2002.01026.x PMid:12190884

PAN, D., MEI, X. 2010. Antioxidant activity of an exopolysaccharide purified from Lactococcus lactis subsp. lactis 12. In Carbohydrate polymers, vol. 80, 2010, p. 908- 914. doi:10.1016/j.carbpol.2010.01.005

PERRIN, S., GRILL, J. P., SCHNEIDER, F. 2000. Effects of fructooligosaccharides and their monomeric components on bile salt resistance in three species of bifidobacteria. In Journal of Applied Microbiology, vol. 88, 2000, p. 968-974. doi:10.1046/j.1365-2672.2000.01070.x PMid:10849172

PICON, A., GARCÍA-CASADO, M. A., NUÑEZ, M. 2010. Proteolytic activities, peptide utilization and oligopeptide transport systems of wild Lactococcus lactis strains. In International Dairy Journal, vol. 20, 2010, p. 156-162. doi:10.1016/j.idairyj.2009.10.002

REDDY, G., ALTAF, MD., NAVEENA, B. J., VENKATESHWAR, M., KUMAR, E. V. 2008. Amylolytic bacterial lactic acid fermentacion - A review. In Biotechnology Advances, vol. 26, 2008, p. 22-34. doi:10.1016/j.biotechadv.2007.07.004 PMid:17884326

RODRIGUES, L. R., TEIXEIRA, J. A., VAN DER MEI, H. C., OLIVEIRA, R. 2006. Physicochemical and functional characterization of a biosurfactant produced by Lactococcus lactis 53. In Colloids and Surfaces B: Biointerfaces, vol. 49, 2006, p. 79-86. doi:10.1016/j.colsurfb.2006.03.003 PMid:16616461

RODRIGUES, L. R., VAN DER MEI, H. C., TEIXEIRA, J. A., OLIVEIRA, R. 2004. Influence of Biosurfactants from Probiotic Bacteria on Formation of Biofilms on Voice Prostheses. In Applied Microbiology and Biotechnology, vol. 70, 2004a, p. 4408-4410. PMid:15240331

RODRIGUES, L. R., VAN DER MEI, H. C., TEIXEIRA, J. A., OLIVEIRA, R. 2004. Biosurfactant from Lactococcus lactis 53 inhibits microbial adhesion on silicone rubber. In Applied Microbiology and Biotechnology, vol. 66, 2004b, p. 306-311. doi:10.1007/s00253-004-1674-7 PMid:15290139

ROHWER, F., EDWARDS, R. 2002. The phage proteomic tree: a genome-based taxonomy for phage. In Journal of Bacteriology, vol. 184, 2002, p.  4529-4535. doi:10.1128/JB.184.16.4529-4535.2002 PMid:12142423

RUAS-MADIEDO, P., TUINIER, R., KANNING, M., ZOON, P. 2002. Role of exopolysaccharides produced by Lactococcus lactis subsp. cremoris on the viscosity of fermented milks. In International Dairy Journal, vol. 12, 2002, p. 689-695. doi:10.1016/S0958-6946(01)00161-3

SALMINEM, S., VON WRIGHT, A., MORELLI, L., MARTEAU, P., BRASSART, D., DE VOS, W. M., FONDÉN, R., SAXELIN, M., COLLINS, K., MOGENSEN, G., BIRKELAND, S. E., MATTILA-SANDHOLM, T. 1998. Demonstration of safety of probiotics - a review. In International Journal of Food Microbiology, vol. 44, 1998, p. 93-106. doi.org/10.1016/S0168-1605(98)00128-7 PMid:9849787

SANTOS, W. C., SOUZA, M. R., CERQUEIRA, M. M. O.  P., GLORIA, M. B. A. 2003. Bioactive amine formation in milk by Lactococcus in the presence or not of rennet andNaCl at 20 and 32 °C. In Food Chemistry, vol. 81, 2003, p. 595-606. doi:10.1016/S0308-8146(02)00502-2

SCHLEIFER, K. H., KRAUS, J., DVORAK, C., KILLPER-BÄLZ, R., COLLINS, M. D., FISCHER, W. 1985. Transfer of Streptococcus lactis and related streptococci to the genus Lactococcus gen. nov. In Systematic and Applied Microbiology, vol. 6, 1985, p. 183-195.

SIRÉN, N., SALONEN, K., LEISOLA, M., NYYSSÖLÄ, A. 2009. A new salt inducible expression system for Lactococcus lactis. In Biochemical Engineering Journal, 2009, vol. 48, p. 132-135. doi:10.1016/j.bej.2009.08.003

SMIT, G., SMIT, B. A., ENGELS, W. J. M. 2005. Flavour formation by lactic acid bacteria and biochemical flavour profiling of cheese products. In FEMS Microbiology Reviews, vol. 29, 2005, p. 591-610. doi:10.1016/j.fmrre.2005.04.002 PMid:15935512

STOKES, D., ROSS, R. P., FITZGERALD, G. F., COFFEY, A. 2001. Application of Streptococcus thermophilus DPC1842 as a adjunct to counteract bacteriophage disruption in a predominantly lactococcal Cheddar cheese starter: use in bulk starter culture systems. In Lait, vol. 81, 2001, p. 327-334. doi:10.1051/lait:2001107

TECHNICAL GUIDANCE. 2008. Update of the criteria used in the assessment of bacterial resistance to antibiotics of human or veterinary importance. In The EFSA Journal, 2008 , 732, p. 1. 1-15.

TEMMERMAN, R., POT, B., HUYS, G., SWINGS, J. 2003. Identification and antibiotic susceptibility of bacterial isolates from probiotic products. In International Journal of Food Microbiology, vol. 81, 2003, p. 1-10. doi:10.1016/S0168-1605(02)00162-9 PMid:12423913

VASILJEVIC, T., SHAH, N. P. 2008.  Probiotics - From Metchnikoff to bioactives. In International Dairy Journal, vol. 18, 2008, p. 714-728. doi:10.1016/j.idairyj.2008.03.004

VOULOUMANOU, E. K., MAKRIS, G. C., KARAGEORGOPOULOS, D. E., FALAGAS, M. E. 2009.  Probiotics for the prevention of respiratory tract infections: a systematic review. In International Journal of Antimicrobial Agents, vol. 34, 2009, p. 197.e1-197e.10. doi:10.1016/j.ijantimicag.2008.11.005 PMid:19179052

WEGENER, H. C. 2003. Antibiotics in animal feed and their role in resistance development. In Current Opinion in Microbiology, vol. 6, 2003, p. 439-445. doi:10.1016/j.mib.2003.09.009 PMid:14572534

WOUTERS, J. T. M., AYAD, E. H. E., HUGENHOLTZ, J., SMIT, G. 2002. Microbes from raw milk for fermented dairy products. In International Dairy Journal, vol. 12, 2002, p. 91-109. doi:10.1016/S0958-6946(01)00151-0

WU, M. H.,  PAN, T. M., WU, Y. J.,  CHANG, S. J., CHANG, M. S., HU, CH.Y. 2010.  Exopolysaccharide activities from probiotic bifidobacterium: Immunomodulatory effects (on J774A.1 macrophages) and antimicrobial properties. In International Journal of Food Microbiology, vol. 144, 2010, p. 104-110. doi:10.1016/j.ijfoodmicro.2010.09.003 PMid:20884069



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